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EXO1 (HRP)
EXO1 (HRP)
品牌： Usbiological
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对比
咨询纯度：
Purified by Protein G affinity chromatography.
反应种属：
Rabbit
产品介绍
产品介绍
产品信息
荧光素标记
免疫原
Recombinant protein corresponding to aa301-600 from human Exonuclease 1 protein.
产品用途
Suitable for use in ELISA. Other applications not tested.
简单描述
5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.
同种型
IgG
克隆类别
Polyclonal
纯度
Purified by Protein G affinity chromatography.
应用
实验应用
Suitable for use in ELISA. Other applications not tested.
推荐用量
Optimal dilutions to be determined by the researcher.
反应种属
Rabbit
交叉反应性
Hu
目标/特异性
Recognizes human EXO1.
背景
别名
Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI), EXO1, EXOI HEX1
制备和贮存
保存方式
-20°C
数据库链接
SwissProt
Q9UQ84
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