EXP 3174 (10 mg)

108185

Potent and selective AT₁ antagonist

436.89

2-Butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid

Potent and selective noncompetitive AT₁ receptor antagonist (IC₅₀ = 37 nM). Reduces blood pressure in a rat model. Active metabolite of losartan potassium (Cat.No. 3798).

≥98% (HPLC)

Soluble to 100 mM in DMSO and to 100 mM in ethanol

CCCCC1=NC(Cl)=C(C(O)=O)N1CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2

C₂₂H₂₁ClN₆O₂

124750-92-1