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F-ara-EdU (2’-Deoxy-2’-fluoro-5-ethynyluridine)
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F-ara-EdU (2’-Deoxy-2’-fluoro-5-ethynyluridine)
品牌： Lumiprobe
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对比
咨询分子式：
C11H11FN2O5
分子量：
270.22
产品介绍
产品介绍
产品信息
商品描述
F-ara-EdU (2′-deoxy-2′-fluoro-5-ethynyluridine) is a synthetic analog of thymidine used to study de novo DNA synthesis and cell proliferation. It is a less cytotoxic alternative for BrdU (5-Bromo-2′-deoxyuridine) and EdU (5-Ethynyl-2′-deoxyuridine).
F-ara-EdU incorporates into replicating DNA during the S-phase of the cell cycle instead of natural thymidine. Metabolic incorporation of F-ara-EdU into DNA can be detected by copper-catalyzed click reaction with fluorescent or biotin-labeled azides.
In contrast to EdU, F-ara-EdU causes little or no cellular arrest or DNA synthesis inhibition. Therefore, F-ara-EdU is ideally suited for pulse-chase experiments aimed at birth-dating DNA in vivo and long-term cell survival estimation.
分子量
270.22
可溶性
in water, DMSO, DMF
外观
off-white powder
背景
分子式
C11H11FN2O5
CAS号
95740-26-4
制备和贮存
保存方式
24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
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