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FBXO3
品牌： Usbiological
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对比
咨询纯度：
Purified by Protein G affinity chromatography.
反应种属：
Rabbit
产品介绍
产品介绍
产品信息
免疫原
Recombinant protein corresponding to aa276-376 from human F-box only protein 3.
产品用途
Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence. Other applications not tested.
简单描述
Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
同种型
IgG
克隆类别
Polyclonal
纯度
Purified by Protein G affinity chromatography.
应用
实验应用
Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence. Other applications not tested.
推荐用量
Western Blot: 1:200-1:5000 Immunohistochemistry: 1:20-1:200 Immunofluorescence: 1:50-1:200 Optimal dilutions to be determined by the researcher.
反应种属
Rabbit
交叉反应性
Hu Mo
目标/特异性
Recognizes human FBXO3. Species Crossreactivity: mouse
背景
别名
F-box only protein 3, FBXO3, FBX3
制备和贮存
保存方式
-20°C
数据库链接
SwissProt
Q9UK99
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