FICOLL PM70 5KG

Application

Specifically intended for use in perfusion media for laboratory studies on dextran-sensitive animals.

Endotoxin Activity Max.

0.12 EU/mg

Estimated shelf life from manufacture date

5 years

Storage conditions

4–30°C

Stability

Stable in alkaline and neutral solutions, but are rapidly hydrolyzed in solution at pH 3, especially at elevated temperature

Physical State

Solid

Physical Form

Spray-dried powder

Molecular Weight (Mr) Max.

~ 8 × 10⁴

Molecular Weight (Mr) Min.

~ 6 × 10⁴

Reactivity and Stability

The reactivity and stability of Ficoll PM70 are determined by its hydroxyl groups and the glycosidic bonds in the sucrose residues. It is stable in alkaline and neutral solutions. At pH values lower than 3, it is rapidly hydrolyzed, especially at elevated temperatures. In neutral solutions, however, Ficoll PM 400 can be sterilized by autoclaving at 110°C for 30 min without degradation. Strong oxidizing and reducing agents should be avoided.

Stokes Radius

~ 5.1

Color

White

Specific Rotation (alpha)20

50°-65°

Intrinsic Viscosity

~ 10

Solubility

It is delivered as a spray-dried powder and is therefore readily soluble in aqueous media when it is added slowly with concomitant stirring. Any lumps formed during this procedure will dissolve fairly quickly. Concentrations up to 50% (w/v) can easily be attained

Certificate of Analysis

Yes