FKTN

Recombinant protein corresponding to aa87-276 from human Fukutin protein.

Suitable for use in ELISA and Western Blot. Other applications not tested.

Glycosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. May interact with and reinforce a large complex encompassing the outside and inside of muscle membranes. Could be involved in brain development.

IgG

Polyclonal

Purified by Protein G affinity chromatography.

Suitable for use in ELISA and Western Blot. Other applications not tested.

Western Blot: 1:1000-1:5000 Optimal dilutions to be determined by the researcher.

Rabbit

Hu

Recognizes human FKTN.

Fukutin (EC 2.-.-.-) (Fukuyama-type congenital muscular dystrophy protein), FKTN, FCMD

O75072