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FOXO4 (Biotin)

产品介绍
产品介绍
产品信息
荧光素标记
免疫原
Synthetic peptide corresponding to aa45-63 from human forkhead box protein O4.

产品用途
Suitable for use in ELISA. Other applications not tested.

简单描述
Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.

同种型
IgG

克隆类别
Polyclonal

纯度
Purified by immunoaffinity chromatography.

应用
实验应用
Suitable for use in ELISA. Other applications not tested.

推荐用量
Optimal dilutions to be determined by the researcher.

反应种属
Rabbit

交叉反应性
Hu

目标/特异性
Recognizes human FOXO4.

背景
别名
Forkhead box protein O4 (Fork head domain transcription factor AFX1), FOXO4, AFX AFX1 MLLT7

制备和贮存
保存方式
-20°C
数据库链接
SwissProt
P98177

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