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产品介绍
产品信息
商品描述
FPI-1523 sodium, a derivative of avibactam, is a potent β-lactamase inhibitor with K d s of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively.FPI-1523 sodium inhibited PBP2 with an IC 50 of 3.2 μM.FPI-1523 sodium has a high level of antibacterial activity. FPI-1523 sodium has considerable antimicrobial activity.
分子量
345.29
纯度
98%
In vitro(体外研究)
FPI-1523 sodium inhibits K12 E. coli K12 and PBP2, with MIC and IC 50 of 4 μg/mL and 0.4 μg/mL, respectively.[1]
FPI-1523 sodium inhibits E. coli BW25113 pGDP-2 transformants either with an empty vector or expressing different β-lactamases, with low MICs (1-2 μM).[1]
背景
分子式
C9H14N4NaO7S
CAS号
1452459-52-7
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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