VPAC2 (AS69)

mouse

VPAC2 抗体 AS69 是小鼠单克隆 IgG1, 在3篇文献中引用，提供 50 µg/500 µl免疫human物种的VPAC2的氨基酸105-122推荐用于 mouse, rat 和 human 来源的VPAC2 WB 和 IF检测目前，我们还没有完成VPAC2 抗体 (AS69)的首选二抗检测试剂的鉴定。这项工作正在进行中。 查看产品引用文献(3) The vasoactive intestinal peptide (VIP) and pituitary adenylate cylase-activating polypeptide (PACAP) belong to a superfamily of peptide hormones that include glucagon, secretin and growth hormone releasing hormone. The effects of VIP and PACAP are mediated by three G-protein coupled receptors, VPAC1, VPAC2 and the PACAP receptor (also designated PAC1-R). The VPAC receptors have equal affinities for VIP and PACAP, which stimulate the activation of adenylyl cyclase. Both VPAC1 and VPAC2 are abundantly expressed in brain and T cells, where they modulate neuronal differentiation and T cell activation, respectively The PACAP receptor is a seven transmembrane protein that produces at least eight isoforms by alternative splicing. Each isoform is associated with a specific signaling pathway and a specific expression pattern. The PACAP receptor, which is thought to play an integral role in brain development, preferentially binds PACAP in order to stimulate a cAMP-protein kinase A signaling pathway (2,7).For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

血管活性肠多肽受体2抗体、500μl磷酸缓冲盐溶液(含0.1%叠氮化钠和0.1%明胶)

HumanVIPR2

WB, IF

7434