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galectin-3 (H-5)

产品介绍
产品介绍
产品信息
宿主
mouse

简单描述
galectin-3抗体(H-5)是小鼠单克隆IgG1 κ, 在2篇文献中引用,规格为200 µg/ml特异性抗原位于human物种的galectin-3的N-terminus的氨基酸2-31之间推荐用于 mouse, rat 和 human 来源的galectin-3 WB, IP, IF, IHC(P) 和 ELISA检测看 galectin-3 (B2C10): sc-32790,可查看有标记的 galectin-3 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790m-IgG Fc BP-HRP, m-IgG1 BP-HRP 和 m-IgGκ BP-HRP 是 galectin-3 Antibody (H-5) for WB and IHC(P) 的首选应用二抗。这些试剂现在以套装形式提供galectin-3 Antibody (H-5)。 (见下方订购信息).
查看产品引用文献(2) Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) inter- actions and play a role in tumor progression, pre-mRNA splicing and apop-tosis. The galectin-3 protein, also known as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. Galectin-3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin-3 is involved in cancer progression and metastasis. Galectin-3 mediates the endocytosis of β1 Integrins in a lactose-dependent manner and is associated with thyroid malignancy and Crohn′s disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
