BV421 Mouse Anti-GATA3(L50-823)

GATA3

Mouse BALB/c IgG1, κ

Conserved peptide between the trans-activation and DNA-binding domains of human, mouse and rat GATA3

GATA3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This ~50-kDa nuclear protein regulates the development and subsequent maintenance of multiple tissues. GATA3 is involved in the development of T lymphocytes (regulates T cell receptor subunit gene expression) and the differentiation of mature T cells to become Th2 cells. The expressed levels of normal or mutant GATA3 are also associated with the behaviors of various cancer cells including estrogen receptor-positive breast carcinoma cells. The L50-823 monoclonal antibody recognizes human and mouse GATA3.

GATA3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This ~50-kDa nuclear protein regulates the development and subsequent maintenance of multiple tissues. GATA3 is involved in the development of T lymphocytes (regulates T cell receptor subunit gene expression) and the differentiation of mature T cells to become Th2 cells. The expressed levels of normal or mutant GATA3 are also associated with the behaviors of various cancer cells including estrogen receptor-positive breast carcinoma cells. The L50-823 monoclonal antibody recognizes human and mouse GATA3.

Mouse BALB/c IgG1, κ

L50-823

Intracellular staining (flow cytometry) (Routinely Tested) Immunofluorescence, Immunocytochemistry (Tested During Development)

5 µl

Human (QC Testing), Mouse (Tested in Development)

Gata-3; GATA binding protein 3; GATA-binding factor 3; HDR

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

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