全部商品分类
GDF-5/BMP-14 Protein, Human
用小程序，查商品更便捷
收藏
对比
咨询28kDa (Non-reducing)
Ala382-Arg501
28kDa (Non-reducing)
50mM HAc, pH2.9
1μg (R: reducing condition, N: non-reducing condition).
Human growth differentiation factor 5 (GDF5) is one of the bone morphogenetic proteins (BMPs) belonging to the transforming growth factor β (TGF-β) superfamily. It has commercial value as a therapeutic protein because of its ability to induce cartilage and bone formation, and angiogenesis in adult animals. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations of GDF5 are associated with several human and animal diseases that are characterized by skeletal deformity such as short digits and short limbs.
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Jin L, Li X. Growth differentiation factor 5 regulation in bone regeneration. Curr Pharm Des. 2013;19(19):3364-73.