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GEMIN6
品牌： Usbiological
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对比
咨询纯度：
Purified by Protein G affinity chromatography.
反应种属：
Rabbit
产品介绍
产品介绍
产品信息
抗原来源
Human
宿主
Rabbit
免疫原
Recombinant protein corresponding to aa1-167 from human Gem-associated protein 6 protein.
产品用途
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.
简单描述
The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
同种型
IgG
克隆类别
Polyclonal
纯度
Purified by Protein G affinity chromatography.
形式
Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
应用
实验应用
E IHC
推荐用量
Immunohistochemistry: 1:20-1:200 Optimal dilutions to be determined by the researcher.
反应种属
Rabbit
交叉反应性
Hu
目标/特异性
Recognizes human GEMIN6.
稀释度
Immunohistochemistry: 1:20-1:200 Optimal dilutions to be determined by the researcher.
背景
别名
Gem-associated protein 6 (Gemin-6) (SIP2), GEMIN6
制备和贮存
保存方式
Storage_Temp:-20°C
Storage_and_Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
UniProt ID
Q8WXD5
SwissProt
Q8WXD5
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