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Glucagon Antibody

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Glucagon Antibody

品牌： CST

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参数

反应种属：

来源宿主：

产品介绍

产品信息

荧光素标记

Unconjugated

抗原名称

Glucagon

来源纯化

Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Tyr62 of human glucagon protein. Antibodies are purified by protein A and peptide affinity chromatography.

宿主

Rabbit

商品描述

Product Usage Information

Application	Dilution
Immunohistochemistry (Paraffin)	1:100 - 1:400
Immunofluorescence (Frozen)	1:200

研究领域

癌症,纤维化,代谢,神经科学,

应用

反应种属

Human,Mouse,Rat,

目标/特异性

Specificity/Sensitivity

Glucagon Antibody detects endogenous levels of total glucagon protein.

Species Reactivity:

Human, Mouse, Rat

敏感性

Endogenous

背景

Glucose homeostasis is regulated by a variety of hormones including glucagon. Glucagon is synthesized as the precursor molecule proglucagon and is proteolytically processed to yield the mature peptide in α cells of the pancreatic islets. Glucagon causes the release of glucose from glycogen and stimulates gluconeogenesis in the liver (1,2). 1.Hers, H.G. and Hue, L. (1983) Annu. Rev. Biochem. 52, 617-653. 2.Granner, D. and Pilkis, S. (1990) J. Biol. Chem. 265, 10173-10176.

研究领域

癌症,纤维化,代谢,神经科学,

翻译后修饰

unmodified

制备和贮存

保存方式

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

数据库链接

Entrez-Gene ID

2641

UniProt ID

P01275

参考图片

Confocal immunofluorescent analysis of normal mouse pancreas using Glucagon Antibody (green). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).

Immunohistochemical analysis of paraffin-embedded human pancreas, showing staining of α cells, using Glucagon Antibody.

Immunohistochemical analysis of paraffin-embedded mouse pancreas, showing staining of α cells, using Glucagon Antibody.

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货号：

2760S

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询价

优宁维现货

100ul

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当前规格1件起购

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