货号： 4336-100-01 品牌： R&D Systems 库存： 国外现货
Poly(ADP-ribose) Polymer/pADPr (100 uL)
Poly [ADP-ribose] Polymer
PARP [Poly(ADP-ribose) Polymerase], also known as ADPRT and PPOL, is a 118-kDa enzyme that uses NAD as a substrate to catalyze the covalent transfer of ADP-ribose to a variety of nuclear protein acceptors. ADP ribosyltransferase is required for cellular repair, and PARP expression is induced by single-strand breaks in DNA. PARP is proteolytically cleaved by Caspase-3 into two fragments of 89- and 24-kDa in one of the hallmark events of apoptosis.
- HT PARP In Vivo Pharmacodynamic Assay II
- Immunotoxin-induced Apoptosis
- PAR & PARP Assays
- PARP Universal Colorimetric Assay