GP 1a (10 mg)

10252734

CB₂ receptor inverse agonist

441.35

N-(Piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide

Highly selective CB₂ receptor agonist; K_i values are 0.037 and 363 nM for CB₂ and CB₁ receptors respectively. Increases P-ERK1/2 expression in HL-60 cells in vitro.

≥99% (HPLC)

Soluble to 100 mM in DMSO and to 100 mM in ethanol

CC1=CC2=C(C=C1)C1=C(C2)C(=NN1C1=CC=C(Cl)C=C1Cl)C(=O)NN1CCCCC1

C₂₃H₂₂Cl₂N₄O

511532-96-0