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GPC1 (FITC)


品牌: Usbiological







纯度:
Purified by Protein G affinity chromatography.
反应种属:
Rabbit
产品介绍
产品介绍
产品信息
荧光素标记
免疫原
Recombinant protein corresponding to aa342-530 from human Glypican-1.

产品用途
Suitable for use in FLISA. Other applications not tested.

简单描述
Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

同种型
IgG

克隆类别
Polyclonal

纯度
Purified by Protein G affinity chromatography.

应用
实验应用
Suitable for use in FLISA. Other applications not tested.

推荐用量
Optimal dilutions to be determined by the researcher.

反应种属
Rabbit

交叉反应性
Hu

目标/特异性
Recognizes human GPC1.

背景
别名
Glypican-1 [Cleaved into: Secreted glypican-1], GPC1

制备和贮存
保存方式
-20°C
数据库链接
SwissProt
P35052

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