GSPT1/ERF3A GST&His Protein, Human

品牌： UA BIOSCIENCE

下载产品说明书

用小程序，查商品更便捷

对比

咨询

参数

分子量：

纯度：

产品介绍

产品信息

荧光素标记

Unconjugated

氨基酸序列

Phe294-Asp499, with C-terminal GST&His

分子量

51kDa (Reducing)

纯度

＞85% by SDS-PAGE

内毒素水平

<0.1EU/μg

性状

Liquid

表达系统

Baculovirus

缓冲体系

50mM Tris, 20mM GSH, 5%Glycerol, pH8.0

种属

Human

电泳JSON

[{"imgUrl":"https://univ-pmc.oss-cn-shanghai.aliyuncs.com/54f07bc5-e9b7-4676-8f8a-a5e5a83ebaaf","description":"

1μg (R: reducing condition, N: non-reducing condition).

"}]

背景

别名

ERF3A;eRF3aFLJ38048;ETF3A;eukaryotic peptide chain release factor GTP-binding subunit ERF3A;Eukaryotic peptide chain release factor subunit 3a;FLJ39067;G1 to S phase transition 1,551G9.2;G1 to S phase transition protein 1 homolog;GST1

背景

GSPT1/ERF3A mediates ETF1/ERF1 delivery to stop codons: The eRF1-eRF3-GTP complex binds to a stop codon in the ribosomal A-site.GTP hydrolysis by GSPT1/ERF3A induces a conformational change that leads to its dissociation, permitting ETF1/ERF1 to accommodate fully in the A-site. Binding of eRF1, eRF3, and GTP to pretermination complexes first induces a structural rearrangement that is manifested as a 2 nucleotide forward shift of the toeprint attributed to pretermination complexes that leads to GTP hydrolysis followed by rapid hydrolysis of peptidyl tRNA.

制备和贮存

保存方式

· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

文献

Cell. 2016 Nov 17;167(5):1229-1240.e15.
Cell. 2006 Jun 16;125(6):1125-36.

数据库链接

Accession

P15170-1

参考图片

1μg (R: reducing condition, N: non-reducing condition).

声明：本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。

货号：

UA010964-100μg

一键复制

询价

25μg

100μg

选择数量

当前规格1件起购

配送至

预计1-2周送达，快递: 免运费，若需干冰额外收费

询价大包装询价