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产品介绍
产品信息
抗原名称
COX-2,NF-κB

商品描述
Guaiacol, a phenolic compound isolated from Guaiac resin, inhibits LPS-stimulated COX-2 expression and NF-κB activation. Anti-inflammatory activity.

分子量
124.14

纯度
>98%

可溶性
DMSO :24 mg/mL (193.33 mM)

外观
Clear colorless to light yellow Liquid

In vitro(体外研究)
Guaiacol inhibits LPS-stimulated nuclear factor kappa B (NF-κB) activation and cyclooxygenase (COX)-2 gene expression in cells of the RAW 264.7 murine macrophage cell line. Phenolic compounds such as Phenol, Eugenol, Guaiacol and Vanillin inhibit sheep vesicular gland prostaglandin cyclooxygenase, as indicated by their 50% inhibition concentrations, which decline in the following order: Phenol (1600 μM) > Vanillin (>500 μM) > Guaiacol (72 μM) > Eugenol (12 μM).

背景
别名
愈创木酚; 2-Methoxyphenol

分子式
C7H8O2

CAS号
90-05-1

制备和贮存
保存方式
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
参考图片
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