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H3B-120
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产品介绍
产品介绍
产品信息
抗原名称
CPS1:1.4 μM (ki), CPS1:1.5 μM
商品描述
H3B-120 is a highly selective, competitive, and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor (IC50: 1.5 μM; Ki: 1.4 μM) with anti-cancer activity.
分子量
372.48
纯度
98%
可溶性
DMSO:62 mg/mL (166.45 mM)
In vitro(体外研究)
H3B-120 (25, 50, 75, 100 μM) inhibits urea production in a dose-dependent manner, although the cellular potency decreases significantly compared with enzymatic assays.?The half-life of H3B-120 is only 40 min.?H3B-120 has no inhibition of CPS2 activity of CAD (CPS2, aspartyl transcarbamylase, dihydroorotase).
背景
分子式
C19H24N4O2S
CAS号
2194903-42-7
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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