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InVivoMAb anti-mouse TIM-1 (CD365)

InVivoMAb anti-mouse TIM-1 (CD365)

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品牌: BioXcell
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反应种属:
mouse
来源宿主:
产品介绍
产品介绍
产品信息
宿主
克隆号
RMT1-10
克隆类别
单抗

Product Details

The RMT1-10 monoclonal antibody reacts with mouse T cell immunoglobulin and mucin domain 1 (TIM-1) also known as CD365. TIM-1 is a type I cell-surface glycoprotein and member of the Ig superfamily. TIM-1 is preferentially expressed on TH2 cells and has been identified as a stimulatory molecule for T cell activation. The TIM gene family, plays critical roles in regulating the immune response to viral infection. TIM-1 is also involved in allergic responses, asthma, and transplant tolerance. The RMT1-10 antibody has been shown to neutralize TIM-1 in vivo and reduce the severity of EAE, in mice studies.

Specifications

Isotype Rat IgG2a, κ
Recommended Isotype Control(s)InVivoMAb rat IgG2a isotype control, anti-trinitrophenol
Recommended Dilution BufferInVivoPure pH 7.0 Dilution Buffer
Conjugation This product is unconjugated. Conjugation is available via our Antibody Conjugation Services.
Immunogen Full-length mouse Tim-1-Ig fusion protein
Reported Applicationsin vivo TIM-1 blockade
Formulation PBS, pH 7.0
Contains no stabilizers or preservatives
Endotoxin <2EU/mg (<0.002EU/μg)
Determined by LAL gel clotting assay
Purity >95%
Determined by SDS-PAGE
Sterility 0.2 µm filtration
Production Purified from cell culture supernatant in an animal-free facility
Purification Protein G
RRIDAB_10949022
Molecular Weight 150 kDa
Storage The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
组成成分
抗TIM-1(细胞表面蛋白)抗体,磷酸盐缓冲液
应用
反应种属
mouse
背景
研究领域
Apoptosis, Cancer Biology, Immune Checkpoint Protein, Immunology
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货号:
BE0113-1MG
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