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品牌: BD Pharmingen
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咨询反应种属:
Human (QC Testing), Rhesus, Cynomolgus, Baboon, Dog, Rabbit (Tested in Development)
来源宿主:
Mouse IgG2b, κ
产品介绍
产品使用步骤推荐 产品介绍
产品信息
荧光素标记
抗原名称
HLA-DR

宿主
Mouse IgG2b, κ

免疫原
Human PBMC and SL6866 Cell Line

简单描述
The TU36 monoclonal antibody specifically binds to a monomorphic epitope on major histocompatibility complex (MHC) Class II HLA-DR antigens expressed on B cells, activated T cells, and antigen presenting cells. The antibody detects the MHC Class II αβ complex and not the isolated α or β chains. This antibody fixes complement.

商品描述
TU36
The TU36 monoclonal antibody specifically binds to a monomorphic epitope on major histocompatibility complex (MHC) Class II HLA-DR antigens expressed on B cells, activated T cells, and antigen presenting cells. The antibody detects the MHC Class II αβ complex and not the isolated α or β chains. This antibody fixes complement.

同种型
Mouse IgG2b, κ

克隆号
克隆 TU36 (also known as Tü36; TÜ36) (RUO)

产品详情
FITC
Fluorescein (FITC) is part of the BD blue family of dyes. This is a small organic fluorochrome with an excitation maximum (Ex Max) at 494-nm and an emission maximum (Em Max) at 518-nm. FITC is designed to be excited by the Blue laser (488-nm) and detected using an optical filter centered near 520 nm (e.g., a 530/30-nm bandpass filter). Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
FITC
494 nm
518 nm
BD化合物表
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应用
实验应用
Flow cytometry (Routinely Tested)

推荐用量
20 µl

反应种属
Human (QC Testing), Rhesus, Cynomolgus, Baboon, Dog, Rabbit (Tested in Development)

目标/特异性
HLA-DR

制备和贮存
存储溶液
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

保存方式
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
文献
文献
研发参考(3)
1. Pawelec G, Ziegler A, Wernet P. Dissection of human allostimulatory determinants with cloned T cells: stimulation inhibition by monoclonal antibodies TU22, 34, 35, 36, 37, 39, 43, and 58 against distinct human MHC class II molecules. Hum Immunol. 1985; 12(3):165-176. (Biology).
2. Ziegler A, Heinig J, Muller C, et al. Analysis by sequential immunoprecipitations of the specificities of the monoclonal antibodies TU22,34,35,36,37,39,43,58 and YD1/63.HLK directed against human HLA class II antigens. Immunobiology. 1986; 171(1-2):77-92. (Biology).
3. Ziegler A, Uchańska-Ziegler B, Zeuthen J, Wernet P. HLA antigen expression at the single cell level on a K562 X B cell hybrid: an analysis with monoclonal antibodies using bacterial binding assays.. Somatic Cell Genet. 1982; 8(6):775-89. (Immunogen).

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