BD Pharmingen™ FITC Mouse Anti-Human HLA-DR

FITC

HLA-DR

Mouse IgG2a, κ

The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.

G46-6 The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.

Mouse IgG2a, κ

克隆 G46-6 (also known as L243) (RUO)

Flow cytometry (Routinely Tested)

20 µl

Human (QC Testing), Rhesus, Cynomolgus, Baboon (Tested in Development), Dog (Reported)

HLA-DR

MHC class II antigen; HLA class II histocompatibility antigen

Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

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