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HSD17B14 (17-beta-hydroxysteroid Dehydrogenase 14, 17-beta-HSD 14, 17-beta-hydroxysteroid Dehydrogenase DHRS10, Dehydrogenase/Reductase SDR Family Mem
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产品介绍
产品介绍
产品信息
纯化方式
Affinity Purified
Purified by Protein A affinity chromatography.
抗原名称
Hsd17b14 protein
免疫原
Full length human HSD17B14, aa1-270 (NP_057330.2).
商品描述
HSD17b14 (hydroxysteroid (17beta)dehydrogenase type 14), also called 17bHSD14 or DHRS10, is a cytoplasmic 17beta hydroxy steroid dehydrogenase that is a member of the SDR (shortchain dehydrogenase/reductase) family. It is a 270aa, ~30kD protein with mRNA highly expressed in brain, placenta, liver and kidney. It converts estradiol to estrone, thus inactivating it, and is thought to regulate activity of estrogens and possibly dihydroepiandrosterone (DHEA) in the placenta and central nervous system. Human HSD17b14 shares 80.5% aa sequence identity with mouse and rat HSD17b14.
形式
Supplied as a liquid in PBS, pH 7.2.
产品类型
Polyclonal
应用
实验应用
Western Blot (WB)
反应种属
Human
背景
别名
Anti -HSD17B14 (17-beta-hydroxysteroid Dehydrogenase 14, 17-beta-HSD 14, 17-beta-hydroxysteroid Dehydrogenase DHRS10, Dehydrogenase/Reductase SDR Family Member 10, Retinal Short-chain Dehydrogenase/Reductase retSDR3, DHRS10, SDR3, UNQ502/PRO474)
制备和贮存
保存方式
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
NCBI
66065
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