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BD OptiBuild™ RY610 Mouse Anti-Human CD16
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品牌： BD Pharmingen
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咨询反应种属：
Human (Tested in Development)
实验应用：
Flow cytometry (Qualified)
产品介绍
产品介绍
产品信息
荧光素标记
免疫原
Human NK Cells
简单描述
The B73.1 monoclonal antibody specifically binds to CD16, the 50-70 kDa low affinity receptor for IgG, IgG Fc receptor III (FcγRIII). CD16 is expressed on NK cells, neutrophils, and on a subset of T cells from certain individuals. The B73.1 antibody binds to CD16-positive neutrophils with lower intensity when compared with some other CD16-specific antibodies. A variable number of CD16-positive lymphocytes coexpress either the CD57 antigen or low-density CD8 antigen or both. The B73.1 antibody can block Fc receptor functions mediated by CD16.
商品描述
B73.1
The B73.1 monoclonal antibody specifically binds to CD16, the 50-70 kDa low affinity receptor for IgG, IgG Fc receptor III (FcγRIII). CD16 is expressed on NK cells, neutrophils, and on a subset of T cells from certain individuals. The B73.1 antibody binds to CD16-positive neutrophils with lower intensity when compared with some other CD16-specific antibodies. A variable number of CD16-positive lymphocytes coexpress either the CD57 antigen or low-density CD8 antigen or both. The B73.1 antibody can block Fc receptor functions mediated by CD16.
同种型
Mouse BALB/c IgG1, κ
克隆号
克隆 B73.1 (RUO)
浓度
0.2 mg/ml
产品详情
RY610
The BD Horizon RealYellow™ 610 (RY610) Dye is part of the BD® family of yellow-green dyes. It is a tandem fluorochrome with an excitation maximum (Ex Max) at 557-nm and an emission maximum (Em Max) at 610-nm as measured using an antibody-dye conjugate. Driven by BD® innovation, RY610 can be used on both spectral and conventional cytometers and is designed to be excited by the Yellow-Green laser (561-nm) with minimal excitation by the 488-nm blue laser. For conventional instruments equipped with a Yellow-Green laser (561-nm), RY610 can be used as an alternative to PE-CF594 and we recommend using an optical filter centered near 610-nm (eg, a 610/20-nm bandpass filter). For spectral instruments equipped with a Yellow-Green laser (561-nm), it can be used in conjunction with PE-CF594.
RY610
Yellow-Green 561 nm
557 nm
610 nm
应用
实验应用
Flow cytometry (Qualified)
反应种属
Human (Tested in Development)
目标/特异性
CD16
背景
别名
IgG Fc receptor III; IGFR3; FCG3; FCGR3; FCGRIII; FcγRIII
制备和贮存
存储溶液
Aqueous buffered solution containing ≤0.09% sodium azide.
数据库链接
Entrez-Gene ID
2214, 2215
参考图片
Multiparameter flow cytometric analysis using BD OptiBuild™ RY610 Mouse Anti-Human CD16 antibody (Cat. No. 759228; Right Plot) on Human peripheral blood lymphocytes, with corresponding IgG Isotype Control (Cat. No. 571151; Left Plot). Flow cytometry was performed using a BD LSRFortessa™ X-20 Flow Cytometer System.
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