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Hu Gma Dta TCR RB744 11F2 25Tst
品牌： BD Pharmingen
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对比
咨询反应种属：
Human (QC Testing)
实验应用：
Flow cytometry (Routinely Tested)
产品介绍
产品使用步骤推荐 产品介绍
产品信息
荧光素标记
RB744()
免疫原
Sepharose® bead/CD3/γ/δ TCR complex
简单描述
The 11F2 monoclonal antibody specifically reacts with a framework epitope of the γ/δ TCR. The γ/δ TCR is a heterodimeric glycoprotein that is noncovalently associated with the CD3 antigen complex. The γ and δ TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ chain forms either disulfide-linked or non-disulfide-linked heterodimers with the δ-subunit. TCR γ/δ is present on a minor subset of T lymphocytes in peripheral blood, thymus, spleen, and lymph node. TCR γ/δ-positive T lymphocytes comprise 1% to 9% of normal peripheral blood lymphocytes and less than 2% of normal thymocytes. The 11F2 antibody is mitogenic for γ/δ-TCR-bearing T lymphocytes.
商品描述
11F2
The 11F2 monoclonal antibody specifically reacts with a framework epitope of the γ/δ TCR. The γ/δ TCR is a heterodimeric glycoprotein that is noncovalently associated with the CD3 antigen complex. The γ and δ TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ chain forms either disulfide-linked or non-disulfide-linked heterodimers with the δ-subunit. TCR γ/δ is present on a minor subset of T lymphocytes in peripheral blood, thymus, spleen, and lymph node. TCR γ/δ-positive T lymphocytes comprise 1% to 9% of normal peripheral blood lymphocytes and less than 2% of normal thymocytes. The 11F2 antibody is mitogenic for γ/δ-TCR-bearing T lymphocytes.
同种型
Mouse BALB/c IgG1
克隆号
克隆 11F2 (RUO)
产品详情
RB744
The BD Horizon RealBlue™ 744 (RB744) Dye is part of the BD® family of blue dyes. It is a tandem fluorochrome with an excitation maximum (Ex Max) at 498-nm and an emission maximum (Em Max) at 746-nm as measured using an antibody-dye conjugate. Driven by BD® innovation, RB744 can be used on both spectral and conventional cytometers and is designed to be excited by the Blue laser (488-nm) with minimal excitation by the 561-nm Yellow-Green laser. For conventional instruments equipped with a Blue laser (488-nm), we recommend using an optical filter centered near 750-nm (e.g., a 750/60-nm bandpass filter).
RB744
498 nm
746 nm
BD化合物表
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应用
实验应用
Flow cytometry (Routinely Tested)
推荐用量
5 µl/test
反应种属
Human (QC Testing)
目标/特异性
TCR γδ
背景
别名
TCRgd; γδ TCR; TRG@/TRD@; TCRG/TCRD; TCR gamma delta
制备和贮存
存储溶液
Aqueous buffered solution containing ≤0.09% sodium azide.
数据库链接
Entrez-Gene ID
6964, 6965
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