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对比
咨询Product Summary
Precision
Serum, EDTA Plasma, Citrate Plasma, Urine
| Intra-Assay Precision | Inter-Assay Precision | |||||
|---|---|---|---|---|---|---|
| Sample | 1 | 2 | 3 | 1 | 2 | 3 |
| n | 20 | 20 | 20 | 40 | 40 | 40 |
| Mean (pg/mL) | 1.31 | 5.32 | 11.4 | 1.51 | 5.71 | 11.1 |
| Standard Deviation | 0.1 | 0.23 | 0.4 | 0.12 | 0.27 | 0.91 |
| CV% | 7.6 | 4.3 | 3.5 | 7.9 | 4.7 | 8.2 |
Recovery
The recovery of FGF basic spiked to three different levels throughout the range of the assay in various matrices was evaluated.
| Sample Type | Average % Recovery | Range % |
|---|---|---|
| Citrate Plasma (n=4) | 97 | 83-118 |
| EDTA Plasma (n=4) | 99 | 85-109 |
| Serum (n=4) | 100 | 88-116 |
| Urine (n=4) | 109 | 100-120 |
Linearity
Scientific Data
Human FGF basic/FGF2/bFGF Quantikine HS ELISA Kit Summary
Background: FGF basic/FGF2/bFGF
FGF basic/FGF2/bFGF is a growth factor that functions in angiogenesis, wound healing, tissue repair, learning and memory, and the morphogenesis of heart, bone, and brain. It is upregulated in response to inflammatory stimuli and in many tumors. FGF basic/FGF2/bFGF binds to FGFR1c and 2c. Its bioactivity is modulated by a number of other binding partners including heparin, Integrin alpha V beta 3, soluble FGFR1, FGF-BP, free gangliosides, Thrombospondin, Pentraxin 3/TSG-14, Fibrinogen, alpha 2-Macroglobulin, PDGF, and CXCL4/PF4. These molecules act as cellular coreceptors or adhesion partners, extracellular matrix decoys or reservoirs, and soluble scavengers or chaperones. In particular, the interaction of FGF basic/FGF2/bFGF with cell surface heparan sulfate proteoglycans (HSPG) is required for the binding and activation of FGF receptors.