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产品介绍
产品信息
氨基酸序列
Protein sequence(P20142, Ala17-Ala387, with C-10*His)
AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMAYMDAAYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTSHSRFNPSESSTYSTNGQTFSLQYGSGSLTGFFGYDTLTVQSIQVPNQEFGLSENEPGTNFVYAQFDGIMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGVDSSLYTGQIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILSNNGYCTVGVEPTYLSSQNGQPLWILGDVFLRSYYSVYDLGNNRVGFATAGGGGSHHHHHHHHHH

分子量
Theoretical:42.1kDa Actual:40kDa

纯度
>95% by SDS-PAGE

内毒素水平
<1EU/μg

性状
Lyophilized powder

表达系统
HEK293

缓冲体系
Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.

标签
His Tag

种属
Human

电泳JSON
[{"imgUrl":"https://univ-sdt.oss-cn-shanghai.aliyuncs.com/prod/202302/f89c4d4335fe42e79a01ef1871e5b79b.jpg","description":"
2μg(R: reducing conditions)
"}]
应用
稀释度
[]
背景
别名
Gastricsin, Pepsinogen C

背景
Gastricsin is an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis.

制备和贮存
溶解方法
Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

保存方式
12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.
数据库链接
Accession
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