

产品介绍
产品介绍
产品信息
宿主
鼠

简单描述
抗-HoxC8 抗体 1H2 是小鼠单克隆 IgG1 κ,HoxC8抗体, 在1篇文献中引用,规格为100 µg/mlraised against amino acids 47-136 representing partial length HoxC8 of human origin推荐用于 mouse, rat 和 human 来源的HoxC8 WB, IP 和 ELISA检测目前,我们还没有完成HoxC8 抗体 (1H2)的首选二抗检测试剂的鉴定。这项工作正在进行中。
查看产品引用文献(1) HoxC8 Antibody (1H2) is a high quality monoclonal HoxC8 antibody (also designated HOX3D antibody) suitable for the detection of the HoxC8 protein of mouse, rat and human origin. HoxC8 Antibody (1H2) is available as the non-conjugated anti-HoxC8 antibody. The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Home-obox region 3 contains at least seven homeoboxes in 160 kb of DNA, including Homoeobox 8 (HoxC8) and Homeobox 3A (Hox3A). Overexpression of the HOXC8 transgene causes cartilage defects, the severity of which depends upon transgene dosage. This abnormal cartilage is characterized by an accumulation of proliferating chondrocytes and reduced maturation. Since HoxC8 is normally expressed in chondrocytes, it may be responsible for skeletal development other than pattern formation in a tissue-specific manner, hypothetically by controlling the progression of cells along the chondrocyte differentiation pathway.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

克隆类别
Replacement monoclonal antibody for: sc-49823, sc-67188.

组成成分
同源盒基因蛋白抗体,磷酸盐缓冲液
