ITGA7, CT

KLH-conjugated synthetic peptide mapping to a fragment of residues within aa1149-1181 of the C-terminal region of human ITGA7.

Suitable for use in ELISA, Western Blot. Other applications not tested.

Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.

IgG

Polyclonal

Purified by Protein A and peptide affinity chromatography.

ITGA7

Suitable for use in ELISA, Western Blot. Other applications not tested.

Western Blot: 1:8000 Optimal dilutions to be determined by the researcher.

Rabbit

Hu

Recognizes human ITGA7.

Integrin alpha-7, Integrin alpha-7 heavy chain, Integrin alpha-7 light chain, Integrin alpha-7 70kD form, ITGA7

3679

Q13683