ICAM-1 (28)

mouse

ICAM-1/CD54 抗体 28 是小鼠单克隆 IgG1，提供 50 µg/0.5 ml 免疫human物种的ICAM-1的氨基酸46-160 推荐用于 human 来源的ICAM-1 WB 和 IP检测 看 ICAM-1/CD54 (G-5): sc-8439，可查看有标记的 ICAM-1/CD54 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790 目前，我们还没有完成ICAM-1/CD54 抗体 (28)的首选二抗检测试剂的鉴定。这项工作正在进行中。 Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play important, yet separate, roles in embryogenesis and development. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the β2α1 and β2αM Integrins. ICAM-2 functions as a ligand for lymphocyte function-associated antigen-1 (LFA-1) and is involved in leukocyte adhesion. ICAM-3 is highly expressed on the surface of human eosinophils and, when bound to ligand, may inhibit eosinophil inflammatory responses and survival. ICAM-4, also known as LW glycoprotein, interacts with Integrins αLβ2, αMβ2, α4β1, the αV family and αIIbβ3, and selective binding to different integrins may be relevant to the pathology in a number of red blood cell associated diseases. Lastly, ICAM-5, expressed on telencephalic neurons, binds CD11a/CD18 and thus may act as an adhesion molecule for leukocyte binding in the central nervous system.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

IGG-免疫球蛋白G型抗体

HumanICAM1

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