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产品介绍
产品介绍
产品信息
抗原名称
PI3K
商品描述
CAL-101 is a selective p110δ inhibitor with IC50 of 2.5 nM; shown to have 40- to 300-fold greater selectivity for p110δ thanp110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR.
分子量
415.42
纯度
>98%
可溶性
Ethanol ：22 mg/mL (53 mM)
DMSO ：77 mg/mL (185.4 mM)
DMSO ：77 mg/mL (185.4 mM)
外观
Powder
In vivo(体内研究)
A significant reduction is observed in the CD11b+Ly6G+ neutrophils from brain homogenates of bothp110δD910A/D910A mice and CAL-101 (40 mg/kg, i.v.) post-treated mice.
背景
别名
Idelalisib; CAL-101, GS-1101; GS 1101; GS1101,CAL101
分子式
C22H18FN7O
CAS号
870281-82-6
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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