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mIFN-a MAb (Cl RMMA- (250 ug)

mIFN-a MAb (Cl RMMA- (250 ug)

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品牌: R&D Systems
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来源宿主:
Rat IgG1
实验应用:
ELISA, Neutralization
产品介绍
产品介绍
产品信息
荧光素标记
纯化方式
Protein A or G purified from hybridoma culture supernatant
抗原名称
IFNA, IFNA2, IFNA2b, IFNalpha, IFN-alpha, IFN-alphaA, INFA2, interferon alpha 2, LeIF D
宿主
Rat IgG1
免疫原
Mouse Interferon alpha
克隆号
RMMA-1

Mouse IFN-alpha Antibody Summary

Species Reactivity
Mouse
Specificity
Neutralizes mouse interferon alpha; binds to mouse interferon alpha
Source
Monoclonal Rat IgG1 Clone # RMMA-1
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse Interferon alpha
Formulation
50mM Sodium Bicarbonate; 0.2M Sodium Chloride, pH 8.0
Endotoxin Level
<1.0 EU per 1 μg of the antibody by the LAL method.
Label
Unconjugated

Applications

Recommended Concentration
Sample
ELISA
Please refer to the PDF datasheet for specifications.
Neutralization

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

应用
实验应用
ELISA, Neutralization
背景
别名
IFNA,IFNA2,IFNA2b,IFNalpha,IFN-alpha,IFN-alphaA,INFA2,interferon alpha 2,LeIF D,Interferon alpha
背景

Background: IFN-alpha

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

References
  1. Asselin-Paturel, C. et al. 2005, J. Exp. Med. 201:1157.
  2. Mellor, A.L. et al. 2005, J. Immunol. 175:5601.
Long Name
Interferon alpha
Entrez Gene IDs
3440 (Human)
Alternate Names
IFNA; IFNA2; IFNA2b; IFNalpha; IFN-alpha; IFN-alphaA; INFA2; interferon alpha 2; LeIF D
制备和贮存
保存方式

Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
After receipt, the product may be stored at -20°C for short-term use (≤ 6 months). For long-term storage, we recommend storing the product at -70°C or below for retention of full activity. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Re-freezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).
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货号:
22100-1
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询价
250ug
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