BD™ Cytometric Bead Array (CBA) Human Th1/Th2/Th17 Cytokine Standards

TH1/2/17

The Human Th1/Th2/Th17 Cytokine Standards contains a mixture of individually lyophilized recombinant proteins made up of recombinant Human Interleukin (IL)-2, IL-4, IL-6, IL-10, IL-17A, Interferon-γ (IFN-γ), and Tumor Necrosis Factor (TNF). The reconstituted Human Th1/Th2/Th17 Cytokine Standards are designed for use as standard controls with the BD™ Cytometric Bead Array (CBA) Human Th1/Th2/TH17 Cytokine Kit (Cat. No.560484). Please refer to the manual included with the BD™ Cytometric Bead Array (CBA) Human Th1/Th2/TH17 Cytokine Kit for further information.

(RUO)

Flow cytometry/immunoassay (Routinely Tested)

Human (QC Testing)

IL-2, IL-4, IL-6, IL-10, IL-17A, IFN-γ, TNF

Lyophilized in an aqueous buffered solution containing BSA and ProClin™ 150.

Development References(4) 1. Cook EB, Stahl JL, Lowe L, et al. Simultaneous measurement of six cytokines in a single sample of human tears using microparticle-based flow cytometry: allergics vs. non-allergics. J Immunol Methods. 2001; 254(1-2):109-118. (Methodology: Cytometric Bead Array). 2. Dotti G, Savoldo B, Takahashi S, et al. Adenovector-induced expression of human-CD40-ligand (hCD40L) by multiple myeloma cells. A model for immunotherapy. Exp Hematol. 2001; 29(8):952-961. (Biology: Cytometric Bead Array). 3. Horowitz A, Newman KC, Evans JH, Korbel DS, Davis DM, Riley EM. Cross-talk between T cells and NK cells generates rapid effector responses to Plasmodium falciparum-infected erythrocytes. J Immunol. 2010; 184(11):6043-6052. (Biology: Cytometric Bead Array). 4. Kawamoto K, Pahuja A, Hering BJ, Bansal-Pakala P. Transforming growth factor beta 1 (TGF-beta1) and rapamycin synergize to effectively suppress human T cell responses via upregulation of FoxP3+ Tregs. Transpl Immunol. 2010; 23(1-2):28-33. (Biology: Cytometric Bead Array).