全部商品分类
IL-18 Protein, Mouse
用小程序，查商品更便捷
收藏
对比
咨询18kDa (Reducing)
Asn36-Ser192
18kDa (Reducing)
20mM Tris, 150mM NaCl, pH8.0
1μg (R: reducing condition, N: non-reducing condition).
Interleukin 18 (IL-18) is a pleiotropic cytokine involved in the regulation of innate and acquired immune response. In the milieu of IL-12 or IL-15, IL-18 is a potent inducer of IFN-gamma in natural killer (NK) cells and CD4 T helper (Th) 1 lymphocytes. However, IL-18 also modulates Th2 and Th17 cell responses, as well as the activity of CD8 cytotoxic cells and neutrophils, in a host microenvironment-dependent manner. IL-18 is a cytokine that stimulates various cell types and has pleiotropic functions. Recently, IL-18 has also been shown to execute specific effects in pancreatic diseases, including acute and chronic pancreatitis, as well as pancreatic cancer.
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
1. Acta Biochim Pol 2016;63(1):59-63.Epub 2016 Feb 17.
2. Int J Mol Sci 2019 Feb 2;20(3):649.