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Alexa Fluor 700 Rat Anti-Mouse IL-17A(TC11-18H10)
品牌： BD Pharmingen
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对比
咨询反应种属：
Mouse (QC Testing)
来源宿主：
Rat LEW, also known as Lewis IgG1, κ
产品介绍
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产品信息
荧光素标记
抗原名称
IL-17A
宿主
Rat LEW, also known as Lewis IgG1, κ
商品描述
The TC11-18H10 monoclonal antibody specifically binds to recombinant and natural mouse IL-17A proteins. IL-17A, also known as CTLA-8, is a T cell-derived cytokine that promotes inflammatory responses. Mouse IL-17A is a proinflammatory cytokine that can induce the release of IL-6 by mouse stromal cells. It has been shown to support the growth of hemopoietic progenitors in vitro; it can also stimulate granulopoiesis in vivo. The TC11-18H10 antibody has been reported to neutralize IL-17A activity. Recent studies have shown that IL-17A is produced by a unique subset of Th17 cells that develop along a pathway distinct from the Th1- and Th2- cell differentiation pathways. The mouse IL-17A cDNA was isolated from a cDNA library generated from TCRαβ+CD4-CD8- thymocytes.
应用
反应种属
Mouse (QC Testing)
背景
别名
IL-17; Il17; IL-17A; Il17a; CTLA-8; Ctla8; Interleukin-17A; interleukin 17A
制备和贮存
保存方式
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
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