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Hu CD25 (IL-2Ra) RB744 M-A251 100Tst
品牌： BD Pharmingen
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对比
咨询反应种属：
Human (QC Testing), Rhesus, Cynomolgus, Baboon (Tested in Development)
实验应用：
Flow cytometry (Routinely Tested)
产品介绍
产品使用步骤推荐 产品介绍
产品信息
荧光素标记
RB744()
免疫原
Phytohemagglutinin stimulated human lymphocytes
简单描述
The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as low-affinity interleukin-2 receptor alpha chain subunit (IL-2Rα). CD25 is expressed on regulatory T cells, activated lymphocytes (T and B), and monocytes. It associates with the IL-2Rβ/CD122 and IL-2Rγ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2Rα is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses.
商品描述
M-A251
The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as low-affinity interleukin-2 receptor alpha chain subunit (IL-2Rα). CD25 is expressed on regulatory T cells, activated lymphocytes (T and B), and monocytes. It associates with the IL-2Rβ/CD122 and IL-2Rγ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2Rα is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses.
同种型
Mouse BALB/c IgG1, κ
克隆号
克隆 M-A251 (RUO)
产品详情
RB744
The BD Horizon RealBlue™ 744 (RB744) Dye is part of the BD® family of blue dyes. It is a tandem fluorochrome with an excitation maximum (Ex Max) at 498-nm and an emission maximum (Em Max) at 746-nm as measured using an antibody-dye conjugate. Driven by BD® innovation, RB744 can be used on both spectral and conventional cytometers and is designed to be excited by the Blue laser (488-nm) with minimal excitation by the 561-nm Yellow-Green laser. For conventional instruments equipped with a Blue laser (488-nm), we recommend using an optical filter centered near 750-nm (e.g., a 750/60-nm bandpass filter).
RB744
498 nm
746 nm
BD化合物表
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应用
实验应用
Flow cytometry (Routinely Tested)
推荐用量
5 µl/test
反应种属
Human (QC Testing), Rhesus, Cynomolgus, Baboon (Tested in Development)
目标/特异性
CD25 (IL-2 Receptor α)
背景
别名
IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55
制备和贮存
存储溶液
Aqueous buffered solution containing ≤0.09% sodium azide.
数据库链接
Entrez-Gene ID
3559
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