Mouse IL-33 Recombinant Protein

品牌： CST

下载产品说明书

下载COA

下载SDS

用小程序，查商品更便捷

对比

咨询

参数

分子量：

反应种属：

展开

产品介绍

产品信息

来源纯化

Recombinant mouse IL-33 was expressed in E. coli and is supplied in a lyophilized form.

宿主

E. coli

简单描述

MW (kDa)	17.7
Purity	A greater than or equal to 90% purity was determined by SDS-PAGE.
Endotoxin	Endotoxin levels are less than or equal to 1 EU / 1 μg mIL-33.
Activity	The bioactivity of recombinant mIL-33 was determined in a D10S cell proliferation assay. The ED50 of each lot is less than or equal to 2 ng/ml.

分子量

17.7

研究领域

纤维化,神经科学,

应用

反应种属

Mouse

背景

IL-33 (Interleukin-33, NF-HEV) is a nuclear cytokine that is part of the IL-1 family (1,2). Originally discovered as the ‘nuclear factor from high endothelial venules,’ it is widely expressed by endothelial cells as well as epithelial barrier tissues (1,5). IL-33 is involved in regulating type 2-associated innate immune responses (2,4). It is the ligand for ST2 which, along with IL-1RAcP, forms the IL-33R signaling complex (2,3). IL-33 functions as an alarmin upon cellular damage or stress, and is associated with allergic inflammation and asthma (5,6). 1.Baekkevold, E.S. et al. (2003) Am J Pathol 163, 69-79. 2.Schmitz, J. et al. (2005) Immunity 23, 479-90. 3.Chackerian, A.A. et al. (2007) J Immunol 179, 2551-5. 4.Smithgall, M.D. et al. (2008) Int Immunol 20, 1019-30. 5.Moussion, C. et al. (2008) PLoS One 3, e3331. 6.Cayrol, C. and Girard, J.P. (2014) Curr Opin Immunol 31, 31-7.

研究领域

纤维化,神经科学,

制备和贮存

保存方式

Mouse IL-33 Recombinant Protein is supplied as lyophilized material that is very stable at -20°C. It is recommended to reconstitute with sterile water at a concentration of 0.1 mg/ml which can be further diluted in aqueous solutions as needed. Addition of a carrier protein (0.1% HSA or BSA) is recommended for long-term storage.

Once in solution, store at 4°C and use within 1 month, or store at -20ºC to -80ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles if storing reconstituted material at -20ºC to -80ºC.

数据库链接

Entrez-Gene ID

77125

UniProt ID

Q8BVZ5

参考图片

The purity of Mouse IL-33 Recombinant Protein was determined by SDS-PAGE of 1 µg reduced (+) and non-reduced (-) recombinant mIL-33 and staining with Coomassie Blue.

声明：本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。

货号：

99162S

一键复制

询价

10ug

选择数量

当前规格1件起购

配送至

预计2-3周送达，快递: 免运费，若需干冰额外收费

询价大包装询价