Product Details

The MH9A4 monoclonal antibody reacts with human IL-9, a pleiotropic cytokine expressed by Th9 cells, Th2 cells, Th17 cells, regulatory T cells, NKT cells, ILC2s, and mast cells. IL-9 promotes mast cell and T cell proliferation, stimulates mast cell accumulation in tissues, promotes ILC survival, enhances class-switching to IgE in B cells and alters haematopoietic progenitor cell activity. Additionally, IL-9 enhances mucus production from airway epithelial cells and alters barrier function in the intestines. IL-9 is thought to contribute to asthma. The MH9A4 antibody does not block the binding of IL-9 to the IL-9 receptor.

Specifications

Isotype	Mouse IgG2b, κ
Recommended Isotype Control(s)	InVivoMAb mouse IgG2b isotype control, unknown specificity
Recommended Dilution Buffer	InVivoPure pH 7.0 Dilution Buffer
Conjugation	This product is unconjugated. Conjugation is available via our Antibody Conjugation Services.
Immunogen	Human IL-9 coupled to ovalbumin
Reported Applications	Flow cytometry ELISA
Formulation	PBS, pH 7.0 Contains no stabilizers or preservatives
Endotoxin	<2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay
Purity	>95% Determined by SDS-PAGE
Sterility	0.2 μM filtered
Production	Purified from cell culture supernatant in an animal-free facility
Purification	Protein A
RRID	AB_2819054
Molecular Weight	150 kDa
Storage	The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.

组成成分

白细胞介素9抗体，磷酸盐缓冲液

应用

反应种属

Human

背景

研究领域

Cytokine and Chemokine, Immunology, Innate Immunity

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货号：

BE0327-1MG

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