Integrin α2 (P1H5)

mouse

Integrin α2/ITGA2/CD49b抗体(P1H5)是小鼠单克隆IgG2b κ, 在21篇文献中引用，规格为200 µg/mlraised against HT1080 fibrosarcoma cells of human origin推荐用于 human 来源的Integrin α2 and the integrin α2/β1 complex IP, IF 和 FCM检测还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM目前，我们还没有完成Integrin α2/ITGA2/CD49b 抗体 (P1H5)的首选二抗检测试剂的鉴定。这项工作正在进行中。 查看产品引用文献(21) Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The sixteen α and eight β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as fibrinogen, or to counter-receptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. Integrin α2 is responsible for adhesion of platelets and other cells to collagens. Modulation of collagen and collagenase gene expression force generation and organization of newly synthesized extracellular matrix.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

IGG-免疫球蛋白G型抗体

HumanITGA2

IP, IF, FCM

3673, 3688