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产品介绍
产品介绍
产品信息
宿主
鼠
克隆号
UC3-10A6
克隆类别
单抗
Product Details
The UC3-10A6 monoclonal antibody reacts with an epitope on the delta chain of the mouse Vγ2 TCR (V gamma 2 T cell receptor). Vγ2 TCR expressing T lymphocytes make up a large proportion of the γδ T cells in late fetal and adult thymus, peripheral lymphoid tissues, lung, intestinal epithelium, and epidermis. The exact function, ligand, and specificity of γδ TCR-expressing T cells are not completely understood. Studies suggest that these cells recognize bacterial ligands and some tumor cells in the context of MHC class I-like gene products and play a role in regulating the immune response during bacterial infection. The UC3-10A6 antibody has been shown to deplete γδ T cells when administered in vivo.Specifications
| Isotype | Armenian Hamster IgG, κ |
|---|---|
| Recommended Isotype Control(s) | InVivoMAb polyclonal Armenian hamster IgG |
| Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
| Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
| Immunogen | G8 mouse T cells |
| Reported Applications | in vivo γδ T cell depletion Flow cytometry |
| Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
| Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
| Purity | >95% Determined by SDS-PAGE |
| Sterility | 0.2 µm filtration |
| Production | Purified from cell culture supernatant in an animal-free facility |
| Purification | Protein G |
| RRID | AB_10950109 |
| Molecular Weight | 150 kDa |
| Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
组成成分
亚美尼亚仓鼠抗T细胞受体蛋白单克隆抗体，磷酸盐缓冲液(抗体是免疫球蛋白,属于生物大分子,无生物安全风险,不具有对人传播传染病风险)
应用
反应种属
mouse
背景
研究领域
Immunology
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