

产品介绍
产品介绍
产品信息
宿主
鼠

克隆号
MAR 18.5

克隆类别
单抗

Product Details
The MAR 18.5 monoclonal antibody reacts with the kappa chain of the rat immunoglobulin light chain. The κ chain is one of two types of polypeptide subunits which make up the immunoglobulin light chain. A typical antibody is composed of two immunoglobulin heavy chains and two immunoglobulin light chains. The κ chain is coded for by V (variable), J (joining) and C (constant) genes. These genes undergo V(D)J recombination to generate a diverse repertoire of immunoglobulins. This antibody is used in combination with rat anti-mouse CD19 and CD22 (clones 1D3 and Cγ34.1) to deplete B cells in vivo.Specifications
Isotype | Mouse IgG2a, κ |
---|---|
Recommended Isotype Control(s) | InVivoMAb mouse IgG2a isotype control, unknown specificity |
Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
Conjugation | This product is unconjugated. Conjugation is available via our Antibody Conjugation Services. |
Immunogen | Soluble rat immunoglobulin |
Reported Applications | in vivo B cell depletion in combination with anti-CD19 (clone 1D3) and anti-CD22 (clone Cy34.1) |
Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
Purity | >95% Determined by SDS-PAGE |
Sterility | 0.2 µm filtration |
Production | Purified from cell culture supernatant in an animal-free facility |
Purification | Protein G |
RRID | AB_10951292 |
Molecular Weight | 150 kDa |
Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |
组成成分
抗大鼠免疫球蛋白轻链抗体,磷酸盐缓冲液

应用
反应种属
rat

背景
研究领域
Immunology
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