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ITGAL / CD11a Antibody (clone 87-6F9, Concentrated) LS-C202003
ITGAL / CD11a Antibody (clone 87-6F9, Concentrated) LS-C202003
品牌： Lifespan
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对比
咨询反应种属：
Mouse
来源宿主：
Mouse
产品介绍
产品介绍
产品信息
纯化方式
Purified
抗原名称
Mouse ITGAL / CD11a
宿主
Mouse
商品描述
CD11a antibody LS-C202003 is an unconjugated mouse monoclonal antibody to mouse CD11a (ITGAL). Validated for Flow and IHC.
产品类型
IgG2b
Monoclonal
应用
实验应用
IHC, IHC-Fr, Flo
推荐用量
IHC
IHC - Frozen
Flow Cytometry
反应种属
Mouse
目标/特异性
CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages with increase in levels on memory T cells. CD11a or LFA-1 has a key role in mediating leukocyte adhesion to endothelium during inflammatory responses through binding to ICAM-1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many T cell functions and immune phenomena. Mol. weight in SDS gels is about 180 kD. Part of heterodimer with CD18 (integrin 9-2). A defect in 9-2 expression results in leucocytes adhesion deficiency (LAD) in which patients suffer from recurring bacterial infections.
背景
别名
ITGAL | CD11A | Integrin alpha-L | LFA-1 alpha | LFA-1A | Integrin gene promoter | Alpha polypeptide) | CD11a antigen | LFA-1 | LFA1A
制备和贮存
保存方式
Store at 2-8°C.
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