全部商品分类
1/2
BD Horizon™ BV711 Hamster Anti-Mouse CD11c
品牌： BD Pharmingen
下载产品说明书 下载SDS
用小程序，查商品更便捷
收藏
对比
咨询反应种属：
Mouse (QC Testing)
来源宿主：
Armenian Hamster IgG1, λ2
产品介绍
产品介绍
产品信息
荧光素标记
抗原名称
CD11c (Integrin aX)
宿主
Armenian Hamster IgG1, λ2
免疫原
C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes
简单描述
The HL3 monoclonal antibody specifically binds to the integrin αx chain of gp150, 95 (CD11c/CD18). CD11c is expressed on dendritic cells, CD4- CD8+ intestinal intraepithelial lymphocytes (IEL) and some NK cells. It is upregulated on IEL and lymph-node T cells following
in vivo
activation. Cells of the monocyte/macrophage lineage have been reported to express low levels of CD11c. CD11c plays a role in binding of iC3b.
商品描述
HL3
The HL3 monoclonal antibody specifically binds to the integrin αx chain of gp150, 95 (CD11c/CD18). CD11c is expressed on dendritic cells, CD4- CD8+ intestinal intraepithelial lymphocytes (IEL) and some NK cells. It is upregulated on IEL and lymph-node T cells following
in vivo
activation. Cells of the monocyte/macrophage lineage have been reported to express low levels of CD11c. CD11c plays a role in binding of iC3b.
同种型
Armenian Hamster IgG1, λ2
克隆号
克隆 HL3 (RUO)
浓度
0.2 mg/ml
产品详情
BV711
The BD Horizon Brilliant Violet™ 711 (BV711) Dye is part of the BD Horizon Brilliant Violet™ family of dyes. This tandem fluorochrome is comprised of a BV421 donor with an excitation maximum (Ex Max) of 407-nm and an acceptor dye with an emission maximum (Em Max) at 713-nm. BV711, driven by BD innovation, is designed to be excited by the violet laser (405-nm) and detected using an optical filter centered near 710-nm (e.g., a 712/20-nm bandpass filter). The acceptor dye can be excited by the Red (628–640-nm) laser resulting in cross-laser excitation and fluorescence spillover. Please ensure that your instrument’s configurations (lasers and optical filters) are appropriate for this dye.
BV711
Violet 405 nm
407 nm
713 nm
应用
实验应用
Flow cytometry (Routinely Tested)
反应种属
Mouse (QC Testing)
目标/特异性
CD11c (Integrin αX)
背景
别名
Cd11c; Itgax; Integrin alpha-X; Integrin αX; Cr4; Complement receptor 4
制备和贮存
存储溶液
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
保存方式
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
文献
文献
研发参考(6)
1. Barclay NA, Brown MH, Birkeland ML, et al, ed. The Leukocyte Antigen FactsBook. San Diego, CA: Academic Press; 1997.
2. Burt BM, Plitas G, Stableford JA, et al. CD11c identifies a subset of murine liver natural killer cells that responds to adenoviral hepatitis. J Leukoc Biol. 2008; 84(4):1039-1046. (Clone-specific: Flow cytometry).
3. Gao JX, Liu X, Wen J, et al. Differentiation of monocytic cell clones into CD8 alpha+ dendritic cells (DC) suggests that monocytes can be direct precursors for both CD8 alpha+ and CD8 alpha- DC in the mouse. J Immunol. 2003; 170(12):5927-5935. (Biology).
4. Huleatt JW, Lefrançois L. Antigen-driven induction of CD11c on intestinal intraepithelial lymphocytes and CD8+ T cells in vivo.. J Immunol. 1995; 154(11):5684-93. (Immunogen: Flow cytometry, Immunoprecipitation).
5. Maraskovsky E, Brasel K, Teepe M, et al. Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified. J Exp Med. 1996; 184(5):1953-1962. (Biology).
6. Pulendran B, Lingappa J, Kennedy MK, et al. Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice. J Immunol. 1997; 159(5):2222-2231. (Biology).
数据库链接
Entrez-Gene ID
16411
参考图片
Flow cytometric analysis of CD11c expression on mouse dendritic cells. C57BL/6 mouse splenocytes were cultured with recombinant mouse GM-CSF (Cat. No.554586; 5 ng/ml) overnight. The cells were then harvested and stained either with a BD Horizon™ BV711 Hamster IgG1, λ1 Isotype Control (Cat. No. 563049; dashed line histogram) or with the BD Horizon™ BV711 Hamster Anti-Mouse CD11c antibody (Cat. No. 563048; solid line histogram). The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable dendritic cells. Flow cytometry was performed using a BD™ LSR II Flow Cytometer System.
声明 ：本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。