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产品介绍
产品介绍
产品信息
抗原名称
Skeletal muscle myosin:1.6 μM, Smooth muscle myosin II:>100 μM, Cardiac muscle myosin:5.4 μM
商品描述
JB062 is a nonmuscle myosin inhibitor with IC 50 values of 1.6, 5.4, and >100 μM for Skeletal muscle myosin , Cardiac muscle myosin , and Smooth muscle myosin II, respectively. JB062 has cytotoxic to human cancer cells but not normal cells. JB062 can be used in research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy .
分子量
323.34
纯度
98%
可溶性
DMSO:22.5 mg/mL (69.58 mM)
In vitro(体外研究)
JB062 (40 μM ; 24 h) inhibited cytoplasmic division in COS-7 cells.[1]
JB062 (COS-7 cells) exhibited cytotoxicity against human cancer cells but showed no cytotoxicity towards normal cells, with an IC50 value of 36 μM.[1]
背景
分子式
C19H17NO4
CAS号
2417988-00-0
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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