L-741,626 (10 mg)

133633

High affinity D₂ antagonist

340.85

3-[[4-(4-Chlorophenyl)-4-hydroxypiperidin-l-yl]methyl-1H-indole

A potent D₂ dopamine receptor selective antagonist, with affinities of 2.4, 100 and 220 nM for D₂, D₃ and D₄ receptors respectively. Centrally active following systemic administration in vivo.

≥98% (HPLC)

Soluble to 100 mM in DMSO and to 100 mM in ethanol

OC1(CCN(CC2=CNC3=CC=CC=C23)CC1)C1=CC=C(Cl)C=C1

C₂₀H₂₁ClN₂O

81226-60-0