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产品介绍
产品介绍
产品信息
抗原名称
OT-R
商品描述
LIT-001 is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM). LIT-001 improves social interaction in a mouse model of autism.
分子量
645.70
纯度
98%
可溶性
DMSO : 250 mg/mL (387.18 mM; Need ultrasonic)
In vitro(体外研究)
In vitro signaling experiments, LIT-001 is a nonbiased OT-R agonist on the two main signaling pathways of this receptor, with minor antagonist effect on V1a and agonist effect on V1b receptors, observed at high concentrations only.
In vivo(体内研究)
LIT-001 (10-20 mg/kg; i.p.) alleviates core symptoms in the context of autism spectrum disorders (ASD ).
背景
分子式
C30H34F3N7O4S
CAS号
2245072-21-1
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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