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产品介绍
产品介绍
产品信息
商品描述
LTC4 (Leukotriene C4), and other leukotrienes, are potent eicosanoid lipid mediators that play numerous roles in inflammation, immunological functions and maintaining biological homeostasis; primarily acting through specific G protein-coupled receptors. This product is a potent arachidonic acid -derived agonist for contraction of smooth muscle and has been shown to induce microvascular permeability and mucus secretion in airways. Furthermore, this product has been shown to enhance growth of human airway epithelial cells, reduce myocardial contractility and coronary blood flow, induce long lasting hypotension, and stimulate angiogenesis. LTC4 (Leukotriene C4) is an inhibitor of MGST.

分子量
625.77

PH值
5.6

可溶性
Soluble in water (100 µg/ml) at 25° C.

浓度
50 µg/ml in methanol/ammonium acetate buffer, 65:35, pH 5.6

外观
A solution in ethanol

IC50
ABCC2 overexpressed: IC50 = 0.15 µM (MDCK cell)

应用
实验应用
A potent agonist for contraction of smooth muscle, wtih many important immunomodulatory functions

背景
分子式
C30H47N3O9S

CAS号
72025-60-6

沸点
78.5° C

MDL
MFCD00151079

折射率
n20D 1.56

制备和贮存
保存方式
Store at -80° C
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