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产品介绍
产品介绍
产品信息
商品描述
LY3372689 is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer‘s disease.
分子量
383.44
纯度
98%
可溶性
DMSO:225.0 mg/mL (586.8 mM)
In vivo(体内研究)
In rat studies, LY3372689 demonstrated a dose-dependent change in OGA EO following a single oral dose with a maximum EO of greater than 90%. A plasma concentration-dependent increase in brain OGA EO was observed with EO exceeding 90% at 24 hours following the highest dose of LY3372689 administered.[1]
背景
分子式
C16H22FN5O3S
CAS号
2241514-56-5
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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