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Lys33-Pro187
18.2 kDa (Reducing)
1μg (R: reducing condition, N: non-reducing condition).
"}]Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), is a hematopoietic growth factor. It can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of several diseases, including breast and endometrial cancers.
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
1. Cosman D, Wignall J, Anderson D, et al. 1988. Behring Inst Mitt: 15-26.
参考图片
1μg (R: reducing condition, N: non-reducing condition).
Measured in a cell proliferation assay using Murine M-NFS-60 cells, the EC50 for this effect is less than 2ng/ml.